René Fontaine / René Fontaine

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Cincuenta años del Servicio de Angiología y Cirugía Vascular del Hospital Universitario Central de Asturias (HUCA) de Oviedo (1963-2013). Primer servicio asistencial y docente de España / Fifty years of the Angiology and Vascular Surgery Department in the Central Asturias University Hospital (HUCA) in Oviedo (1963-2013). First healthcare and teaching department in Spain

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Lower limb vascular dysfunction in cyclists / Disfunções vasculares em membros inferiores de ciclistas

Sports-related vascular insufficiency affecting the lower limbs is uncommon, and early signs and symptoms can be confused with musculoskeletal injuries. This is also the case among professional cyclists, who are always at the threshold between endurance and excess training. The aim of this review was to analyze the occurrence of vascular disorders in the lower limbs of cyclists and to discuss possible etiologies. Eighty-five texts, including papers and books, published from 1950 to 2012, were used. According to the literature reviewed, some cyclists receive a late diagnosis of vascular dysfunction due to a lack of familiarity of the medical team with this type of dysfunction. Data revealed that a reduced blood flow in the external iliac artery, especially on the left, is much more common than in the femoral and popliteal arteries, and that vascular impairment is responsible for the occurrence of early fatigue and reduced performance in cycling.

O desenvolvimento de insuficiência vascular em membros inferiores relacionada à prática esportiva é incomum e no início do surgimento dos sinais e sintomas frequentemente pode ser confundida com lesão musculoesquelética, a exemplo de casos relatados em ciclistas profissionais, por estarem sempre no limiar entre o treinamento em nível máximo e o excesso de treinamento. O objetivo desta revisão de literatura foi analisar a ocorrência de disfunções vasculares em membros inferiores em ciclistas e as possíveis etiologias. Oitenta e cinco textos, entre artigos e livros publicados de 1950 a 2012 foram utilizados. Segundo a literatura, alguns ciclistas têm o diagnóstico de disfunção vascular realizado tardiamente devido à falta da familiaridade da equipe médica com esta modalidade de disfunção. Os resultados da pesquisa revelaram que a redução do fluxo sanguíneo na artéria ilíaca externa, em especial a esquerda, é bem mais comum que a da artéria femoral e poplítea, e que o comprometimento vascular é responsável pela ocorrência de fadiga precoce e redução do desempenho no ciclismo.

The path from art to evidence in treating critical limb ischaemia--reflections on 35 years' experience.

Despite numerous attempts, chronic critical limb ischaemia (CLI) has not been unequivocally defined as yet. Its epidemiology is poorly investigated and its prevalence probably higher than anticipated. It is accompanied by high mortality and morbidity irrespective of the way it is treated. Its management is very expensive. Additionally, the prevailing diabetes epidemic is increasing the need for revascularizations although there is a clear lack of evidence as to when to revascularize an ulcerated diabetic foot. The fast development of endovascular techniques blurs the vision as the window of opportunity for gathering proper evidence keeps narrowing. The notion of endovascular artistry prevails, but attempts to conduct proper studies with clear definitions, strict criteria and appropriate outcome measures in a standardised manner should continue--preferably using propensity scoring if randomised controlled trials are not possible. This review highlights some of the steps leading from art to evidence and illustrates the difficulties encountered along the path. In parallel with this overview, the progress of the treatment for CLI in Finland is described from the perspective of the work concluded at Helsinki University Central Hospital.

Idiopathic polypoidal choroidal vasculopathy (IPCV). 1990.

Eleven patients, 40 to 71 years old, had a choroidal vasculopathy that led to hemorrhagic and exudative macular degeneration. The patients had peculiar polypoidal, subretinal, vascular lesions associated with serous and hemorrhagic detachments of the retinal pigment epithelium. This macular disorder, which we have named idiopathic polypoidal choroidal vasculopathy (IPCV), appears to represent a distinct entity that differs clinically and demograph-ically from age-related macular degeneration (AMD) and other macular diseases associated with subretinal neovascularization. Recognition of this condition is important because it may have specific risk factors, natural course, and management considerations that differ from those of age-related macular degeneration

Treatment of polypoidal choroidal vasculopathy with photodynamic therapy. 2002.

PURPOSE: To study the effects of photodynamic therapy using verteporfin in the treatment of patients with subfoveal polypoidal choroidal vasculopathy (PCV). METHODS: A retrospective chart review of 16 consecutive patients with subfoveal PCV treated with photodynamic therapy using verteporfin was performed. RESULTS: The mean age of the patients involved was 70.5 years. The mean follow-up time was 12 months. The visual acuity improved in 9 (56.3 %), remained the same in 5 (31.3 %), and decreased in 2 (12.5 %). The mean change in visual acuity was an improvement of 2.38 lines, a difference that was highly significant (P = 0.004). The change in visual acuity was negatively correlated with increasing age. The final visual acuity was positively correlated with initial acuity and negatively correlated with age. These results were confirmed by multiple linear regression. No patient had any lasting complication from the treatment. CONCLUSIONS: Subfoveal PCV has no proven method of treatment. Although the follow-up time and the number of patients in this pilot study were limited, the encouraging results and lack of complications suggest that further study is indicated.

Past, present and future of femoropopliteal stenting.

Endovascular stent implantation was introduced to femoropopliteal procedures almost 2 decades ago. Initial results with balloon-expandable stainless steel stents and self-expanding Elgiloy stents, however, were disappointing. In particular, recurrence rates after long-segment femoropopliteal stenting were catastrophically high, in the range of 60% to 80% at 1 year. Also, attempts to resolve the problem of in-stent restenosis (ISR) using first-generation covered stent-grafts led to unsatisfactory results, high procedural complication rates due to large introducers, and a high incidence of graft thrombosis, which did not make these devices convincing alternatives to bare metal stents. After years of stagnation, however, recent developments in femoropopliteal stent technology have been promising. Self-expanding nitinol stents have been evaluated in several prospective studies. Initial problems with stent fractures seem to be resolved using second-generation devices; for the first time, stenting has been shown to be beneficial compared to balloon angioplasty in longer femoropopliteal lesions. Nevertheless, although superior to balloon angioplasty, nitinol stenting is still associated with a considerable restenosis rate, and treatment of ISR remains problematic. Future concepts to further improve long-term patency after femoropopliteal stenting therefore are under investigation, including drug-eluting stents, biodegradable stents, and coated stent-grafts. From a current perspective, femoropopliteal stenting remains the Achilles' heel of the interventionist.

Historia de la angiología y cirugia vascular en Cuba / History of angiology and vascular suergery in Cuba

El autor realiza una descripción y análisis del desarrollo de la Angiología y Cirugía Vascular en Cuba con aportaciones de referencias de personajes y acontecimientos a lo largo de la historia desde sus comienzos hasta el momento actual (AU)

The author makes a description and analysis of the development of the Angiology and Vascular Cirugía in Cuba with contributions of references of personages and events to releases it of history from its beginnings to the present moment (AU)

[Physical diagnostics--peripheral arterial diseases]. / Fysische diagnostiek--perifeer arterieel vaatlijden.

In a patient with a high a priori risk of peripheral vascular disease, the positive predictive value of an abnormal physical diagnostic examination is high. In patients with a low prior probability of peripheral vascular disease, the physical examination makes little contribution to the diagnosis or exclusion of arterial insufficiency. For this purpose the ankle-brachial systolic pressure index is preferable. Peripheral arterial disease is unlikely when this index is normal. However, a low ankle-brachial index necessitates further investigations to determine possible arterial insufficiency in the lower extremities.

What was the disease of the legs that afflicted King Asa?

BACKGROUND/OBJECTIVE: The elderly have suffered from pain in their legs, which may be associated with various diseases, for thousands of years. This report analyzes the disease that afflicted the biblical King Asa (the third king of the house of Judah who reigned between 867 and 906 BCE). RESULTS: The sentence 'Nevertheless in the time of his old age he was diseased in his legs' indicates that King Asa suffered from disease in his legs. Among numerous diseases, peripheral vascular disease, gout, and degenerative osteoarthritis were most likely to affect the King's legs. And among these diseases, the diagnosis of peripheral vascular disease is the most acceptable. CONCLUSION: This report shows that the roots of contemporary modern gerontology can be traced back to biblical times.

Computed tomographic angiography: historical perspective and new state-of-the-art using multi detector-row helical computed tomography.

Since its clinical introduction in 1991, volumetric computed tomography scanning using spiral or helical scanners has resulted in a revolution for diagnostic imaging. In addition to new applications for computed tomography, such as computed tomographic angiography and the assessment of patients with renal colic, many routine applications such as the detection of lung and liver lesions have substantially improved. Helical computed tomographic technology has improved over the past eight years with faster gantry rotation, more powerful X-ray tubes, and improved interpolation algorithms, but the greatest advance has been the recent introduction of multi detector-row computed tomography scanners. These scanners provide similar scan quality at a speed gain of 3-6 times greater than single detector-row computed tomography scanners. This has a profound impact on the performance of computed tomography angiography, resulting in greater anatomic coverage, lower iodinated contrast doses, and higher spatial resolution scans than single detector-row systems.